WHO Classification of Tumours of the Digestive Systemis the third volume of the Fourth Edition of the WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. This book also provides user-friendly algorithmic approaches to the diagnosis of the major tumors of the digestive tract. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, incidence, age and sex distribution, location, clinical signs and symptoms, pathology, genetics, and predictive factors. The book, prepared by more than 100 authors from 22 countries, contains some 700 color photographs, numerous tables and figures and more than 3700 references.