Contributors |
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xi | |
Consultants to the Editors |
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xvii | |
Preface |
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xxi | |
Preface to the First Edition |
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xxiii | |
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SECTION I GENERAL PRINCIPLES |
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1 | (136) |
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Pharmacokinetics and Pharmacodynamics: The Dynamics of Drug Absorption, Distribution, Action, and Elimination |
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1 | (40) |
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Membrane Transporters and Drug Response |
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41 | (30) |
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71 | (22) |
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93 | (24) |
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The Science of Drug Therapy |
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117 | (20) |
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SECTION II DRUGS ACTING AT SYNAPTIC AND NEUROEFFECTOR JUNCTIONAL SITES |
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137 | (180) |
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Neurotransmission: The Autonomic and Somatic Motor Nervous Systems |
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137 | (46) |
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Muscarinic Receptor Agonists and Antagonists |
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183 | (18) |
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Anticholinesterase Agents |
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201 | (16) |
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Agents Acting at the Neuromuscular Junction and Autonomic Ganglia |
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217 | (20) |
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Adrenergic Agonists and Antagonists |
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237 | (60) |
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5-Hydroxytryptamine (Serotonin): Receptor Agonists and Antagonists |
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297 | (20) |
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SECTION III DRUGS ACTING ON THE CENTRAL NERVOUS SYSTEM |
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317 | (312) |
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Neurotransmission and the Central Nervous System |
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317 | (24) |
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341 | (28) |
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369 | (18) |
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Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium |
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387 | (14) |
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401 | (28) |
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Drug Therapy of Depression and Anxiety Disorders |
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429 | (32) |
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Pharmacotherapy of Psychosis and Mania |
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461 | (40) |
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Pharmacotherapy of the Epilepsies |
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501 | (26) |
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Treatment of Central Nervous System Degenerative Disorders |
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527 | (20) |
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547 | (44) |
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591 | (16) |
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Drug Addiction and Drug Abuse |
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607 | (22) |
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SECTION IV AUTACOIDS: DRUG THERAPY OF INFLAMMATION |
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629 | (108) |
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Histamine, Bradykinin, and Their Antagonists |
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629 | (24) |
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Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor |
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653 | (18) |
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Analgesic-Antipyretic Agents; Pharmacotherapy of Gout |
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671 | (46) |
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Pharmacotherapy of Asthma |
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717 | (20) |
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SECTION V DRUGS AFFECTING RENAL AND CARDIOVASCULAR FUNCTION |
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737 | (230) |
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737 | (34) |
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Vasopressin and Other Agents Affecting the Renal Conservation of Water |
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771 | (18) |
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789 | (34) |
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Treatment of Myocardial Ischemia |
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823 | (22) |
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845 | (24) |
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Pharmacotherapy of Congestive Heart Failure |
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869 | (30) |
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899 | (34) |
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Drug Therapy for Hypercholesterolemia and Dyslipidemia |
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933 | (34) |
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SECTION VI DRUGS AFFECTING GASTROINTESTINAL FUNCTION |
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967 | (54) |
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Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease |
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967 | (16) |
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Willemijntje A. Hoogerwerf |
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Treatment of Disorders of Bowel Motility and Water Flux; Antiemetics; Agents Used in Biliary and Pancreatic Disease |
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983 | (26) |
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Pharmacotherapy of Inflammatory Bowel Disease |
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1009 | (12) |
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SECTION VII CHEMOTHERAPY OF PARASITIC INFECTIONS |
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1021 | (74) |
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Chemotherapy of Protozoal Infections: Malaria |
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1021 | (28) |
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Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections |
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1049 | (24) |
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Chemotherapy of Helminth Infections |
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1073 | (22) |
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SECTION VIII CHEMOTHERAPY OF MICROBIAL DISEASES |
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1095 | (220) |
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General Considerations of Antimicrobial Therapy |
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1095 | (16) |
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Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections |
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1111 | (16) |
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Penicillins, Cephalosporins, and Other β-Lactam Antibiotics |
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1127 | (28) |
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1155 | (18) |
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Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents |
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1173 | (30) |
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Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy |
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1203 | (22) |
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1225 | (18) |
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Antiviral Agents (Nonretroviral) |
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1243 | (30) |
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Antiretroviral Agents and Treatment of HIV Infection |
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1273 | (42) |
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SECTION IX CHEMOTHERAPY OF NEOPLASTIC DISEASES |
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1315 | (90) |
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1315 | (90) |
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SECTION X IMMUNOMODULATORS |
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1405 | (28) |
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Immunosuppressants, Tolerogens, and Immunostimulants |
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1405 | (28) |
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SECTION XI DRUGS ACTING ON THE BLOOD AND THE BLOOD-FORMING ORGANS |
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1433 | (56) |
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Hematopoietic Agents: Growth Factors, Minerals, and Vitamins |
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1433 | (34) |
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Blood Coagulation and Anticoagulant, Thrombolytic, and Antiplatelet Drugs |
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1467 | (22) |
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SECTION XII HORMONES AND HORMONE ANTAGONISTS |
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1489 | (190) |
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Pituitary Hormones and Their Hypothalamic Releasing Factors |
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1489 | (22) |
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Thyroid and Antithyroid Drugs |
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1511 | (30) |
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1541 | (32) |
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1573 | (14) |
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Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormones |
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1587 | (26) |
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Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas |
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1613 | (34) |
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Agents Affecting Mineral Ion Homeostasis and Bone Turnover |
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1647 | (32) |
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1679 | (60) |
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Dermatological Pharmacology |
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1679 | (28) |
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SECTION XIV OPHTHALMOLOGY |
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1707 | (32) |
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1739 | (150) |
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Principles of Toxicology and Treatment of Poisoning |
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1753 | (1) |
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Heavy Metals and Heavy-Metal Antagonists |
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1753 | (136) |
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I. Principles of Prescription Order Writing and Patient Compliance |
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1777 | (10) |
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II. Design and Optimization of Dosage Regimens; Pharmacokinetic Data |
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1787 | (102) |
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Index |
|
1889 | |