This book constitutes the refereed proceedings of the 11th IFIP WG 5.5 Working Conference on Virtual Enterprises, PRO-VE 2010, held in St. Etienne, France, in October 2010. The 91 revised papers were carefully selected from numerous submissions. They are organized in topical sections on sustainability, innovation networks, carbon efficient value networks, management of CNs in humanitarian organizations, collaborative network implementation, collaborative health networks, networking structures, partner selection and VO creation, modeling and managing competencies, trust and information, service orientation in collaborative networks, collaboration process models, performance and value, collaborative work environments, learning and collaboration, virtual communities and teams, inter-organizational information systems for CNs, semantic interoperability for VO, and game theory for CN.