Basic and Clinical Pharmacology
by Katzung, Bertram G.Edition: 10th
Format: Paperback
Pub. Date: 2006-12-05
Publisher(s): McGraw-Hill Medical
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Summary
The current science of pharmacology-and its clinical applications-at your fingertips Now in its 25th year of publication, Basic and Clinical Pharmacology is the most up-to-date and complete pharmacology textbook available. Through nine previous editions it has set the standard for concise and easy-to-read, yet comprehensive coverage of pharmacology. The text's integration of basic with clinical science makes it well suited for an integrated organ-system-based curricula as well as the more traditional curricula. Features In-depth coverage of key pharmacology topics, from basic principles to pharmacologic considerations for autonomic, cardiovascular-renal, smooth muscle, CNS, endocrine, antimicrobial, and chemotherapeutic and immunotherapeutic drugs Updated with dozens of new, recently approved drugs, including monoclonal antibodies Detailed review of the mechanism of action and toxicities of traditional and newer drugs Critical discussions of treatment strategies and recommended drugs for all major diseases Valuable section on toxicology that provides an introduction to occupational and environmental toxicology; heavy metal intoxication and chelators; and management of the poisoned patient Ready-to-use, study-enhancing features, including special interest boxes, lists of common preparations, and dosage information Unique evidence-based chapters on abused drugs; special aspects of perinatal, pediatric, and geriatric pharmacology; and over-the-counter drugs, herbal medications, and nutritional supplements More than 500 concept-clarifying illustrations and tables throughout
Table of Contents
Basic & Clinical Pharmacology
I. BASIC PRINCIPLES
1. Introduction
2. Drug Receptors & Pharmacodynamics
3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Tiem Course of Drug Action
4. Drug Biotransformation
5. Basic & Clinical Evaluation of New Drugs
II. AUTONOMIC DRUGS
6. Introduction to Autonomic Pharmacology
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs
8. Cholinoceptor-Blocking Drugs
9. Adrenoceptor-Activating & Other Sympathomimetic Drugs
10. Adrenoceptor Antagonist Drugs
III. CARDIOVASCULAR-RENAL DRUGS
11. Antihypertensive Agents
12. Vasodilators & the Treatment of Angina Pectoris
13. Drugs Used in Heart Failure
14. Agents Used in Cardiac Arrhythmias
15. Diuretic Agents
IV. DRUGS WITH IMPORTANT ACTIONS ON SMOOTH MUSCLE
16. Histamine, Serotonin, & the Ergot Alkaloids
17. Vasoactive Peptides
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
19. Nitric Oxide, Donors, & Inhibitors
20. Drugs Used in Asthma
V. DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM
21. Introduction to the Pharmacology of CNS Drugs
22. Sedative-Hypnotic Drugs
23. The Alcohols
24. Antiseizure Drugs
25. General Anesthetics
26. Local Anesthetics
27. Skeletal Muscle Relaxants
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
29. Antipsychotic Agents & Lithium
30. Antidepressant Agents
31. Opioid Analgesics & Antagonists
32. Drugs of Abuse
VI. DRUGS USED TO TREAT DISEASES OF THE BLOOD, INFLAMMATION, & GOUT
33. Agents Used in Anemias; Hematopoietic Growth Factors
34. Drugs Used in Disorders of Coagulation
35. Agents Used in Hyperlipidemia
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout
VII: ENDOCRINE DRUGS
37. Hypothalamic & Pituitary Hormones
38. Thyroid & Antithyroid Drugs
39. Adrenocorticosteroids & Adrenocortical Antagonists
40. The Gonadal Hormones & Inhibitors
41. Pancreatic Hormones & Antidiabetic Drugs
42. Agents That Affect Bone Mineral Homeostasis
VIII: CHEMOTHERAPEUTIC DRUGS
43. Beta-Lactam Antibodies & Other Inhibitors of Cell Wall Synthesis
44. Chloramphenicol. Tetracyclines, Macrolides, Clindamycin, & Streptogramins
45. Aminoglycosides & Spectinomycin
46. Sulfonamides, Trimethoprim, & Quinolones
47. Antimycobacterial Drugs
48. Antifungal Drugs
49. Antiviral Agents
50. Miscellaneous Antimicrobial Drugs: Disinfectants, Antiseptics, & Sterilants
51. Clinical Use of Antimicrobial Agents
52. Basic Principles of Antiparasitic Chemotherapy
53. Antiprotozoal Drugs
54. Clinical Pharmacology of the Anthelmintic Drugs
55. Cancer Chemotherapy
56. Immunopharmacology
IX. TOXICOLOGY
57. Introduction to Toxicology: Occupational & Environmental
58. Heavy Metal Intoxication & Chelators
59. Management of the Poisoned Patient
X. SPECIAL TOPICS
60. Special Aspects of Perinatal & Pediatric Pharmacology
61. Special Aspects of Geriatric Pharmacology
62. Dermatologic Pharmacology
63. Drugs Used in Gastrointestinal Diseases
64. Therapeutic & Toxic Potential of Over-the-Counter Agents, Botanicals, and Nutritional Supplements
Appendix I. Vaccines, Immune Globulins, & Other Complex
Biologic Products
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